RCDomeThe dome is the visual signature: its cupola rim carries the 53 canonicalized RCD-related entities as nodes colored by their adjudicated ontological level — L1 modalities (19, gold), L2 subtypes (7, blue), L3 triggers (2, green), L4 Functional/contextual (13, purple), and L5 Generic/umbrella/taxon (12, orange) — over a constellation of the 9,265 HGNC-validated genes. Only 19 of the 53 entities are bona fide RCD modalities; the rest are subtypes, triggers, contextual programs, or umbrella concepts, and the level color encodes that distinction.

A multi-database human gene atlas of regulated cell death

9,265 HGNC-validated genes · 53 canonicalized RCD-related entities · 21,568 unique gene–RCD pairs · 20 resources

Hover an entity node on the dome border to reveal its genes · hover a gene dot in the constellation beneath to reveal its RCD entities · click a legend level to highlight

Explore RCDome

Guided tour of the atlas and its evidence layers.

Operational Definitions

The 53 canonicalized RCD-related entities with adjudicated definitions.

Compare Definitions

Side-by-side comparison of 2–4 entities.

RCD entities

The 53 entities with figures, references and summaries.

Gene Catalog

22,473 gene–RCD associations with full provenance.

Discrepancy Radar

The 7,892 classifier-disagreement hotspots, with GPT arbitration and human adjudication.

Discovery Timeline

The 53 entities by founding year, 1859 to 2025, one lane per ontological level.

RCDome Board

Governed DeepSeek synthesis of any entity or gene.

Network

The death core and its regulatory network.

3D RCDome

A rotatable 3D sphere of the 53 entities and their gene constellations.

About

Who built RCDome, related platforms, data provenance.

Contact

Contact the developers.